Lipids as Biomarkers of Brain Disorders

Lipids as Biomarkers of Brain Disorders

Whilst the role of lipids has been particularly relevant within cardiovascular disease, their abundance in the body and high prevalence in several pivotal organs makes them novel biomarkers for many brain disorders. Lipids comprise up to 60% of the dry weight of the brain and have distinct structural attributes that allows them to contribute to many physiological functions, such as energy storage, transportation, and the formation of cell membranes. In the brain, lipids are responsible for impulse conduction, insulation, neurogenesis, and synaptogenesis. Importantly, lipids are vital in the formation of the myelin sheath, which encases all neurons, permitting signal transmittance.

Th17 Cells and IL-17: a possible link between inflammation and neuronal decline in Multiple Sclerosis

Th17 Cells and IL-17: a possible link between inflammation and neuronal decline in Multiple Sclerosis

Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease of the central nervous system (CNS). A major component of the immunopathology of MS is the T cell-driven inflammatory attack from the peripheral immune system towards the CNS.

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