Vaccine Development Solutions
Advanced end-to-end solutions underpinning the development of vaccines to combat infectious diseases
Unrivalled Expertise in Vaccine Development
Synexa Life Sciences offers a comprehensive array of solutions designed to assess the efficacy and immunogenicity of vaccine candidates. Our vaccine services are meticulously designed to investigate both cellular and humoral immune responses, providing a holistic view of vaccine efficacy.
Utilising advanced techniques such as flow cytometry, MHC multimer analysis, and cutting-edge immunoassays, we enable customers to delve deeply into the immune responses elicited by vaccines. Through rigorous evaluations, we empower customers with the critical data needed to make informed decisions, facilitating the development of vaccines that are both safe and effective.
Our Vaccine Services
Serum Proteomics
Gain a systemic view of immune activation and signaling pathways with high-throughput proteomic analysis.
- Olink proteomics platform to quantify expression levels of up to 92 immune-related proteins in serum, enabling biomarker discovery and mechanistic insights
Cellular Immunogenicity
Our cellular assays provide deep insights into T cell-mediated immunity, which is critical to long-term protection and vaccine efficacy.
- Measurement of vaccine-specific T cell responses using ELISpot or FluoroSpot
- Flow cytometry for comprehensive profiling of antigen-specific T cells through intracellular cytokine staining (ICS), activation-induced markers (AIM), and proliferation assays
- Multimer staining for high-resolution detection of antigen-specific T cells
Humoral Immunogenicity
We provide advanced solutions to evaluate vaccine-induced antibody responses, ensuring robust assessment of humoral immunity.
- Quantification of vaccine-specific immunoglobulins using ligand-binding ELISA and MSD platforms
- B Cell ELISpot for precise measurement of antigen-specific B cell activity
- Cell-based neutralisation assays (e.g., reporter and pseudovirus systems) for accurate detection of neutralising antibodies
Synexa's Parntership With CEPI
Synexa is proud to be a member of the Coalition for Epidemic Preparedness Innovations’ (CEPI) Clinical Laboratory Network and Global Central Laboratory Network Advisory Council (GCAC), supporting CEPI’s global initiative to accelerate vaccine development and improve worldwide epidemic preparedness.
Our extensive clinical network supports CEPI by enabling access to convalescent samples for in vitro assessment of vaccine antigen immunogenicity.
Laboratory Solutions for Vaccine Clinical Trials
Learn more about our vaccine services and expertise.
A Complete Vaccine Laboratory Solution
Synexa has partnered with Cytespace Laboratories Africa to provide a complete end-to-end solution for vaccine development. Our combined expertise offers a comprehensive service, from central lab and safety marker analysis to intricate biomarker and bioanalysis, ensuring samples are prepared and processed to their fullest potential.
Improving the quality of human health
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