Flow Cytometry Assay Services

Robust, bespoke flow cytometry assays designed to your specific requirements.

Illuminating Insights

At Synexa we create robust, bespoke flow cytometry panels, custom-designed to meet customer-specific needs and requirements.

We offer a comprehensive suite of advanced assays, including immunophenotyping assays, target engagement PK/PD assays as well as an array of functional assays. Our flow cytometry assays are validated according to the highest standards, including the Clinical and Laboratory Standards Institute’s (CLSI) H62 Validation of Assays Performed by Flow Cytometry guidelines, ensuring that our assays deliver accurate, reproducible results and meet regulatory requirements and best practices.

Our global lab capabilities extend to processing clinical samples from diverse matrices (fresh or cryopreserved) and are strategically positioned to ensure customers receive high-quality, scientifically robust clinical data to advance their drug development pipelines.

Analytical Assay Capabilities:

Each of our assays can be fully customised according to needs and endpoint objectives. Synexa offers full sample management throughout the complete analytical cycle, with dedicated project, logistics and sample management policies.

Lymphocytes (TN, TH, TFH, Treg, TEFF, TEM, TCM, NK & B cells)
Dendritic cells (DCs)
Monocytes
Macrophages
Myeloid-derived suppressor cells (MDSCs)
Multimers
Intracellular staining
Treg polarisation assessment

Receptor occupancy assays
Phospho-flow assays
Polyamine uptake assessment
SARS-CoV-2 immune response assessment
Flow cytometry-based PK assessment

Cytokine expression
Cytotoxic markers
Activation markers
Proliferation assays
Basophil degranulation
Rare cell detection and quantification
Antibody-dependant cellular cytotoxicity (ADCC)
Complement-dependant cytotoxicity (CDC)
Small particle detection and analysis

Robust Flow Cytometry Platforms

In the development of your custom flow cytometry assays, we use technology platforms that are robust, reliable and reputable in the clinical field and provide comprehensive and detailed data readouts for your application.