Synexa Insights
The Latest Insights From Our Scientists
Synexa raises awareness for Rare Diseases Day
28 February 2022 marks Rare Disease Awareness Day and here at Synexa Life Sciences we are sharing our colours to raise awareness for the rare…
Behind The Wave: The Importance of Post-Market Surveillance and its Pertinence to the COVID-19 Pandemic
The world has become engrossed in the vaccine development process since the world’s researchers began their race to provide a…
The Biomarker Association between Depression and Vascular Disease
Major depressive disorder (MDD) has repeatedly emerged as a confounding or prognostic factor in the development of cardiovascular pathologies and…
Infertility and the importance of the endometrial immune balance
Infertility is defined by the World Health Organisation as the inability of a sexually active non-contracepting couple, to conceive after…
Immunogenicity 101: Antidrug Antibodies, Neutralising Antibodies, and everything in between
Protein-based biotherapeutic/biologic agents, such as fusion proteins and monoclonal antibodies (mAb) have become the treatment of choice for many indications…
Th17 Cells and IL-17: a possible link between inflammation and neuronal decline in Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease of the central nervous system (CNS). A major component of the…
Spot on: Use of Dried Blood Spots (DBS) for serological immunoassays
Serological immunoassays provide a complementary approach to PCR-based molecular diagnostics in the detection and monitoring of the immune response of…
Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain
Inflammatory pain and hyperalgesia are considered functional features of an immune response, intended to protect tissue from further damage. At…
The prospect of immunotherapy for combating Alzheimer’s disease
Alzheimer’s disease is a progressive incurable neurodegenerative disorder that often leads to dementia, loss of motor function and cognitive decline.…
Rapid expansion of Treg cells protects from collateral colitis following a viral trigger
Regulatory T (Treg) cells are important for the induction and maintenance of peripheral tolerance; therefore, they are key in preventing…
Immune biomarkers in depression
The identification of clinically relevant and reproducible biomarkers in the field of psychiatry has received increased attention recently in order…
Faecal Calprotectin as a biomarker in Crohn’s disease
Crohn’s disease is an inflammatory bowel disease, which causes inflammation of your digestive tract with symptoms such as abdominal pain,…
Immune checkpoint inhibitors and MDSCs
The development of immune checkpoint inhibitors (ICIs) targeting lymphoid cells has remarkedly transformed therapeutic approaches for the treatment of cancer.…
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