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Protein Degraders: Small Molecules Taking out the Trash

A single PROTAC molecule has two different binding ligands attached by a linker. One ligand binds to the target protein and the other recruits an…

What are Immune Checkpoint Inhibitors?

Diseases, especially cancer, suppress the immune system and compromise the body’s biological mechanisms needed to defend itself from the disease…

Fibrosis and SMAD signalling

During normal physiological wound healing, inflammation, angiogenesis and fibrogenesis are all effectively controlled, so that once sufficient matrix has accumulated…

Lipids as Biomarkers of Brain Disorders

Whilst the role of lipids has been particularly relevant within cardiovascular disease, their abundance in the body and high prevalence…

Synexa raises awareness for Rare Diseases Day

28 February 2022 marks Rare Disease Awareness Day and here at Synexa Life Sciences we are sharing our colours to…

The Biomarker Association between Depression and Vascular Disease

Major depressive disorder (MDD) has repeatedly emerged as a confounding or prognostic factor in the development of cardiovascular pathologies and…

Infertility and the importance of the endometrial immune balance

Infertility is defined by the World Health Organisation as the inability of a sexually active non-contracepting couple, to conceive after…

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