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Protein Degraders: Small Molecules Taking out the Trash
March 4, 2026
A single PROTAC molecule has two different binding ligands attached by a linker. One ligand binds to the target protein and the other recruits an…
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Faecal Calprotectin as a biomarker in Crohn’s disease
July 24, 2020
Crohn’s disease is an inflammatory bowel disease, which causes inflammation of your digestive tract with symptoms such as abdominal pain,…
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Immune checkpoint inhibitors and MDSCs
July 16, 2020
The development of immune checkpoint inhibitors (ICIs) targeting lymphoid cells has remarkedly transformed therapeutic approaches for the treatment of cancer.…
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Potential concussion biomarkers discovered in circulating blood after brain injury
July 16, 2020
Concussions are a commonly diagnosed injury in many sports, particularly at college or professional levels. While the diagnosis of a…
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Complement C4 Genes and Sex-Biased Disease Susceptibility
July 16, 2020
There are many examples of diseases in which there is a sex bias, however, the underlying biology of this bias…
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A unifying expression signature for SLE
July 16, 2020
Systemic Lupus Erythematosus (SLE) is an inflammatory autoimmune condition characterised by a wide variety of symptoms including skin rashes, oral…
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