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The Silence of the Genes: Unlocking Antisense Oligonucleotide Therapies for the Renin-Angiotensin-Aldosterone System

The field of gene therapy is rapidly evolving, with antisense oligonucleotide therapies emerging as powerful tools for modulating gene expression.…

Rapid expansion of Treg cells protects from collateral colitis following a viral trigger

Regulatory T (Treg) cells are important for the induction and maintenance of peripheral tolerance; therefore, they are key in preventing…

Immune biomarkers in depression

The identification of clinically relevant and reproducible biomarkers in the field of psychiatry has received increased attention recently in order…

Faecal Calprotectin as a biomarker in Crohn’s disease

Crohn’s disease is an inflammatory bowel disease, which causes inflammation of your digestive tract with symptoms such as abdominal pain,…

Immune checkpoint inhibitors and MDSCs

The development of immune checkpoint inhibitors (ICIs) targeting lymphoid cells has remarkedly transformed therapeutic approaches for the treatment of cancer.…

Potential concussion biomarkers discovered in circulating blood after brain injury

Concussions are a commonly diagnosed injury in many sports, particularly at college or professional levels. While the diagnosis of a…

Complement C4 Genes and Sex-Biased Disease Susceptibility

There are many examples of diseases in which there is a sex bias, however, the underlying biology of this bias…

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