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From Detection to Decision: Risk-Based Immunogenicity Testing

Immunogenicity describes treatment‑induced B‑ and T‑cell responses to therapeutics and represents a major hurdle for drug development, due to the potential impact on patient safety…

From Pathways to Proof: Targeted Phosphoproteomics and PTM Analysis with LC-MS/MS

Quadrupole mass spectrometry (LC-MS/MS) has long established itself as the workhorse of bioanalysis for small molecules, valued for its high…

Establishing Biosimilarity: Regulatory and Scientific Expectations

A biosimilar is defined as a biologic product, highly similar to a reference or originator, with no clinically meaningful differences…

Why The Future Of Precision Medicine Will Be Defined By The Quality And Strategy Of Biomarker Signatures

We’re in the midst of a paradigm shift in biomarker science. No longer academic luxuries or exploratory afterthoughts, biomarker signatures…

Radiopharmaceutical Drug Development: A Bioanalytical Lab Perspective

The radiopharmaceutical industry has traditionally experienced steady but modest growth, primarily driven by its established role in diagnostics and nuclear…

Building a bioanalytical workflow for a vaccine study: The key assays and considerations

The COVID-19 pandemic put vaccines under the spotlight again, and from a scientific perspective at least, innovations have abounded.…

Quantitative Analysis of Oligonucleotides: An out of the box LC-MS/MS approach

Oligonucleotide therapeutics have revolutionised the field of medicine over the last decade due to their potential for treating a broad…

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