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Why Preclinical Formulation Analysis is Critical to Successful Drug Development

Preclinical studies are designed to establish the safety profile and biological activity of a therapeutic candidate before human testing can begin. The interpretation of these…

Radiopharmaceutical Drug Development: A Bioanalytical Lab Perspective

The radiopharmaceutical industry has traditionally experienced steady but modest growth, primarily driven by its established role in diagnostics and nuclear…

Building a bioanalytical workflow for a vaccine study: The key assays and considerations

The COVID-19 pandemic put vaccines under the spotlight again, and from a scientific perspective at least, innovations have abounded.…

Quantitative Analysis of Oligonucleotides: An out of the box LC-MS/MS approach

Oligonucleotide therapeutics have revolutionised the field of medicine over the last decade due to their potential for treating a broad…

The Next Frontier for CAR T-Cell Therapy: Shifting Gears to Autoimmune Conditions

CAR T-cell therapy has transformed cancer treatment, offering new hope for patients with aggressive B cell malignancies like acute lymphoblastic…

Identifying biomarkers of success: Integrated bioanalysis for glioblastoma CAR-T cell clinical trials

Glioblastoma remains one of the most aggressive and treatment-resistant cancers. Standard therapies often fail, leaving patients with limited options.…

Allogeneic CAR-T Cell Therapies: A major step forward

In a groundbreaking clinical trial, three individuals suffering from severe autoimmune diseases have entered remission following a novel CAR T…