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Why Preclinical Formulation Analysis is Critical to Successful Drug Development

Preclinical studies are designed to establish the safety profile and biological activity of a therapeutic candidate before human testing can begin. The interpretation of these…

A controlled detonation: Targeted antibody drug conjugates (ADCs) for oncology

Are antibody-drug conjugates (ADCs), principally comprised of an antibody, a cytotoxic payload and a linker, the next therapeutic modality of…

The mpox outbreak: Variants, transmission and the boost for vaccine manufacturers

Following Covid-19, the world is collectively on high alert for anything that could indicate another pandemic. What do we know…

The STING Effect: How Biomarkers Expose Harmful Immune Responses

In this latest blog, we explore this pathway, its burgeoning links to multiple diseases and how biomarker profiling can assist…

Falling drug approval rates: What should we be doing differently?

Over the years, this failure rate of drug approvals has not seen significant improvement, which begs the question - why?…

Patient Derived Organoids: Shaping the Fight Against Paediatric Brain Cancer

We highlight some of the exciting translational tools that have been developed to understand brain cancer and how these are…

Advancements in Antibody Therapies for Multiple Sclerosis

Multiple Sclerosis (MS) is a devastating autoimmune disease, characterised by neuronal inflammation which damages the myelin sheath, causing the demyelination…