Flow Cytometry
Robust, bespoke assays designed to your specific requirements.
- Services
- Flow Cytometry
Illuminating Insights
At Synexa we create robust, bespoke flow cytometry assays, customised to meet specific needs and requirements.
We offer a comprehensive suite of advanced assays, including multimer, phospho-flow cytometry and receptor occupancy assays. Our capabilities extend to processing clinical samples from diverse matrices, whether freshly collected or cryopreserved for future batch processing. Moreover, our facilities feature dedicated PBMC processing units and are connected to BSL2-level cell culture laboratories, ensuring the highest standards of sample handling and analysis.
Our team of expert scientists consistently demonstrate excellence and reliability in multimer analysis by participating in the Immudex Proficiency Panel, consistently achieving above average or higher in the proficiency scheme.
Analytical Assay Capabilities:
Each of our assays can be fully customised according to needs and endpoint objectives.
Synexa offers full sample management throughout the complete analytical cycle, with dedicated project, logistics and sample management policies.
- Immuno-profiling & Phenotyping Assays
- Lymphocytes (TN, TH, TFH, Treg, TEFF, TEM, TCM, NK & B cells)
- Dendritic Cells (DCs)
- Monocytes
- Macrophages
- Myeloid-derived suppressor cells (MDSCs)
- Multimers
- Intracellular staining
- Treg polarisation assessment
- Target Engagement/PK/PD Assays
- Receptor Occupancy assays
- Phospho-flow assays
- Polyamine uptake assessment
- SARS-CoV-2 immune response assessment
- Flow cytometry-based PK assessment
- Functional Assays
- Cytokine expression
- Cytotoxic markers
- Activation markers
- Proliferation assays
- Basophil degranulation
- Rare cell detection and quantification
- Antibody-dependant cellular cytotoxicity (ADCC)
- Complement-dependant cytotoxicity (CDC)
- Small particle detection and analysis
Robust and Proven Platforms
Our technology platforms are robust, reliable and reputable in the clinical field and provide comprehensive and detailed data readouts for your application.
CytoFLEX (13 colours)
Platform
BD FACSCanto II (8 colours)
Platform
BD FACSymphony A3 (28 colours)
Platform
Revvity Wizard² Gamma Counter
Platform
Olink®Signature Q100
Platform
illumina iSeq100
Platform