Vectors are objects which have both magnitude and direction.
April 22, 2022
Fibrosis and SMAD signalling
During normal physiological wound healing, inflammation, angiogenesis and fibrogenesis are all effectively controlled, so that once sufficient matrix has accumulated in
Lipids as Biomarkers of Brain Disorders
Whilst the role of lipids has been particularly relevant within cardiovascular disease, their abundance in the body and high prevalence in several pivotal organs makes them novel biomarkers for many brain disorders. Lipids comprise up to 60% of the dry weight of the brain and have distinct structural attributes that allows them to contribute to many physiological functions, such as energy storage, transportation, and the formation of cell membranes. In the brain, lipids are responsible for impulse conduction, insulation, neurogenesis, and synaptogenesis. Importantly, lipids are vital in the formation of the myelin sheath, which encases all neurons, permitting signal transmittance.
March 24, 2022
Synexa raises awareness for Rare Diseases Day
28 February 2022 marks Rare Disease Awareness Day and here at Synexa Life Sciences we are sharing our colours to raise awareness for the rare disease community.
February 28, 2022
The Biomarker Association between Depression and Vascular Disease
Major depressive disorder (MDD) has repeatedly emerged as a confounding or prognostic factor in the development of cardiovascular pathologies and other common lifestyle diseases such as diabetes and obesity
February 15, 2021
Infertility and the importance of the endometrial immune balance
Infertility is defined by the World Health Organisation as the inability of a sexually active non-contracepting couple, to conceive after 12 months of regular intercourse, or to remain pregnant following conception.
February 15, 2021
Th17 Cells and IL-17: a possible link between inflammation and neuronal decline in Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease of the central nervous system (CNS). A major component of the immunopathology of MS is the T cell-driven inflammatory attack from the peripheral immune system towards the CNS.
September 18, 2020
Spot on: Use of Dried Blood Spots (DBS) for serological immunoassays
Serological immunoassays provide a complementary approach to PCR-based molecular diagnostics in the detection and monitoring of the immune response of individuals exposed to a pathogen. In addition to providing valuable information on the seroprevalence of infection, these tests also provide insight into the development and duration of immunity in convalescent individuals. This information is essential for the development of intervention strategies, which shed light on questions surrounding the spread of the disease and identify individuals at risk of reinfection.